Pain
6 videos · updated daily
2:28 Emails to Prescribers on Drug Monitoring: A Randomized Trial
JAMA Network summarizes a randomized trial in JAMA Health Forum in which clinicians sent reminder emails were more likely to use Minnesota's prescription drug monitoring program, with legally framed emails having larger effects and prescribing unchanged.
56:23 Psychedelics for IBS: Inside the First Clinical Trial with Erin Mauney, MD
Dr. Erin Mauney, a pediatric gastroenterologist and researcher at Harvard and Massachusetts General Hospital, on one of the first clinical trials of psilocybin-assisted therapy for patients with treatment-resistant IBS.
27:43 Cebranopadol and Acute Pain Trial Design
James Hackworth, PhD, cebranopadol development lead at Tris Pharma, explains on the Xtalks podcast how cebranopadol targets the NOP receptor alongside opioid pathways, and how bunionectomy and abdominoplasty models serve as pain models in trials.
1:06:48 Designing Paediatric Adaptive Trials with Simulation
Dr. Anna Heath presents two adaptive clinical trials of pain relief in the paediatric emergency department, a dose-ranging study and a comparative effectiveness study, both designed with simulations in R and an R Shiny interface.
19:21 Psilocybin Clinical Trial for Chronic Pain
Jarred Younger of the University of Alabama at Birmingham describes a clinical trial of psilocybin for chronic pain, which in February 2024 was set to run through that year.
1:04:58 KOOS: 30 Years of a Knee Outcome Measure in Studies
Prof. Ewa Roos, developer of the Knee Injury and Osteoarthritis Outcome Score (KOOS), gives Mapi Research Trust an overview of the patient-reported outcome measure, focusing on its interpretability and use in clinical studies.