Clinical Trials 101
46 videos · last 6 months shuffled daily, then older videos newest first
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22:39 Sarcoma Exchange 2026: Clinical Trial Basics with Hope Ventricelli of CISCRP
Hope Ventricelli of CISCRP covers the fundamentals — trial phases, informed consent, the protections in place for patients, and what taking part actually involves.
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55:03 Early Phase Trials in Ovarian and Gynecologic Cancers
Debra Richardson, MD, Chief of Gynecologic Oncology at the University of Oklahoma, explains how first-in-human Phase I studies work, which therapies are in early development and how precision medicine is shaping ovarian cancer care, for Ovarcome.
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1:10:53 Clinical Research Basics for the Down Syndrome Community
Annie Cohen, Ph.D., of University of Pittsburgh Medical Center and Kate O'Neill, Vice President of Community Engagement at NDSS, introduce the basics of clinical research for Down syndrome self-advocates and caregivers, including how to read research articles.
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43:57 Cochrane Lecture: Randomized Controlled Trials
Dr. Ana, Chief Resident in Internal Medicine at the University of São Paulo Clinical Hospital, explains how randomized controlled trials are designed, why randomization matters and how to appraise them, in a Cochrane Early Career Professionals lecture.
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40:09 Next Steps After the Alector Trial in GRN FTD
Behavioral neurologist Dr. Chow explains for Cure GRN how clinical trials and endpoints work, what the completed Alector trial gave the GRN-related FTD field, what participants can learn after a trial and how to join a new one.
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43:07 July 29, 2026 - Understanding Clinical Trials: What to Expect as a Participant
Dr. Lau explains the phases of clinical trials and what to expect as a participant, in a Neuromuscular Disease Foundation session.
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33:57 Sickle Cell Gene Therapy and Trials: Patient Session
Suzi Lowi, a clinical trials research nurse at Imperial College Healthcare NHS Trust, explains what is involved in gene therapy at a West London HCC sickle cell patient event, with audience questions.
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26:06 Kidney Cancer Clinical Trials: What Patients Should Expect
Ben Garmezy, MD, explains what participating in a kidney cancer clinical trial involves, when to consider one, and misconceptions about placebos, leaving a study and experimental treatments, for the Judy Nicholson Kidney Cancer Foundation.
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37:41 Wilson Disease Symposium: Clinical Trials and Gene Therapy
The second session of the Wilson Disease Association and University of Michigan 2026 Spring Support Symposium covers improving neurological symptoms, understanding clinical trials, working with a trial support team, and gene therapy clinical trials.
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28:04 Sarcoma Exchange 2026: How to Make an Informed Decision with Denise Reinke
Philip Leider of the Sarcoma Alliance and Denise Reinke of the Sarcoma Patient Advocacy Global Network walk through the questions to ask when deciding whether a trial is right for you.
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7:55 "Clinical Trials 101" by University of Colorado's Dr. Breelyn Wilky (2020)
University of Colorado medical oncologist Dr. Breelyn Wilky introduces clinical trials — the goals and structure of each phase, and what patients should consider before signing on.
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26:01 How Do Clinical Trials Work?
Roswell Park's Smarter Than Cancer follows an acute myeloid leukemia drug from early research through clinical trials to FDA approval with Dr. Eunice Wang, covering who can take part and how researchers judge safety.
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2:02 Episode 7: What Actually Happens in a Clinical Trial?
Biomea Fusion walks through the clinical trial process from Phase I to Phase III and how researchers evaluate safety and effectiveness before a treatment can be reviewed for approval.
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1:00:54 How Cancer Research Becomes Treatment: Trials Explained
An OCRA panel including Roisin O'Cearbhaill, MD, and Alessia Baccarini, PhD, explains how cancer drugs move from laboratory to approval, covering trial phases, consent, safety oversight and eligibility, with an ovarian cancer survivor on joining a trial.
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32:01 Episode 3: How Clinical Trials Work
Dr. Shruti Naik is joined by physician-scientists Dr. Tom Marron and Dr. Fanny Elahi to explore how clinical trials work and why they underpin modern medicine.
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50:58 Sickle Cell: Clinical Trials Discussion at Patient Day
Suzy Lowi, Senior Clinical Research Practitioner in the Non-Malignant Haematology Clinical Trials Unit at Imperial College Healthcare NHS Trust, presents and discusses clinical trials at a sickle cell patient day run with the NIHR.
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1:00:10 How RECOVER-TLC Clinical Trials Work
The Foundation for the National Institutes of Health presents an overview of how RECOVER-TLC clinical trials work, the steps taken to protect participant safety, and how findings can affect clinical practice, for people considering taking part.
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29:59 Jean-Sébastien Gosuin on Patient-Centred Digital Research
Jean-Sébastien Gosuin, founder of Curewiki, discusses how digital innovation and patient-led insights can address barriers to clinical trial participation, including distance from study sites, for mdgroup.
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24:09 Sarcoma Exchange 2026: Finding Trials You're Eligible For with Dr. Diego Barrenechea of Massive Bio
Dr. Diego Barrenechea of Massive Bio covers the search tools available to patients — from ClinicalTrials.gov to AI-assisted matching services — and how eligibility criteria work.
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22:55 Cancer Trial Enrollment: Awareness Is Not Access
Dr. Matthew Hadfield and Melissa Cutrona discuss the barriers that keep eligible cancer patients out of clinical trials, including placebo misconceptions, rigid eligibility criteria, travel and monitoring burdens, for Oncology Data Advisor.
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1:11 Your Rights and Informed Consent in Clinical Trials
The Pulmonary Vascular Research Institute explains informed consent for people with pulmonary hypertension considering a trial, including the right to ask questions, take time to decide and withdraw at any time.
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22:23 Sarcoma Exchange 2026: Logistics of Enrolling & Participating with Dr. Josep Garcia from INHIBRX
Dr. Josep Garcia of INHIBRX covers the practical side of enrolling and participating — screening and consent, study visits and scheduling, what's expected of participants, and the support available along the way.
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4:29 Dr. Ritesh Kotecha on What to Expect from a Kidney Cancer Clinical Trial
Dr. Ritesh Kotecha of Memorial Sloan Kettering Cancer Center explains what patients can expect when considering a kidney cancer clinical trial, the enrollment process, and why trials need not wait until standard options are exhausted, for KidneyCAN.
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1:56 FDA Approval of a Duchenne Gene Therapy Developed at Nationwide
Nationwide Children's Hospital reports FDA approval of a gene therapy for Duchenne muscular dystrophy developed there, with principal investigator Jerry Mendell, MD, describing the single-infusion clinical trial in boys with DMD.